Running its course quotes:

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I wanted to make sure that this be the first scientific and technology revolution in history in which the public thoroughly discussed all the potential benefits and all the potential harms, in advance of the technology coming online and running its course. -- Jeremy Rifkin
Everything runs its course. We had told a lot of stories that happened in our life. My kid was getting older, and we were running out of stories to tell. -- Howie Mandel

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