different between unsex vs desex

English

un- +? sex

unsex (third-person singular simple present unsexes, present participle unsexing, simple past and past participle unsexed)

To deprive of sexual attributes or characteristics.
- 1603-06, William Shakespeare, Macbeth, Act I, Scene V:
  Lady Macbeth: "Come, you spirits / That tend on mortal thoughts! unsex me here, / And fill me from the crown to the toe full / Of direst cruelty:"
- 1859, George Meredith, The Ordeal of Richard Feverel, Chapter 1:
  The Amazon cut off a breat to battle: How will not Woman disfigure and unsex herself to gain her end?
To sterilize (deprive of the ability to procreate); to castrate.

de- +? sex

desex (third-person singular simple present desexes, present participle desexing, simple past and past participle desexed)

(transitive) To remove another's sexual characteristics or functions, often physical sterilization.

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