different between thiouracil vs goitrogen

English

Etymology

thio- +? uracil

Noun

thiouracil (plural thiouracils)

1. (organic chemistry) Any of a class of heterocycles based on 2-thioxo-1H-pyrimidin-4-one; the parent compound interferes with the synthesis of thyroxine and is used in the treatment of hyperthyroidism

Derived terms

• methylthiouracil
• propylthiouracil

Translations

• Italian: tiouracile (it) f

English

Etymology

Coined some time between 1945 and 1950, from goitre +? -o- +? -gen.

Pronunciation

• IPA^(key): /????t??d??n/, /-?d??n/

Noun

goitrogen (plural goitrogens)

1. Any agent that causes goiter, such as thiouracil.
   • "We have previously shown that treating rats with the reversible goitrogen 6-propyl-2-thiouracil (PTU) from birth to Day 25 increases testis size and sperm production in adulthood by up to 80% and 140%, respectively."
   • "These results suggest that excess iodine induces thyroid involution in goitrogen-treated rats at least partially by apoptosis."

Derived terms

• goitrogenic

References