different between fretfulness vs disquietude

English

fretful +? -ness

fretfulness (usually uncountable, plural fretfulnesses)

From dis- +? quietude.

disquietude (usually uncountable, plural disquietudes)

(uncountable) A state of disquiet, uneasiness, or anxiety.
- 1795, "The Life of John Bunyan," in the Collins Clear-Type Press ed. of The Pilgrim's Progress, p. xiv:
  He was at length called forth, and set apart by fasting and prayer to the ministerial office, which he executed with faithfulness and success during a long course of years; though frequently with the greatest trepidation and inward disquietude.
(countable) A fear or an instance of uneasiness.

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