Lester Grinspoon quotes:

Cannabis is remarkably safe. Although not harmless, it is surely less toxic than most of the conventional medicines it could replace if it were legally available. Despite its use by millions of people over thousands of years, cannabis has never caused an overdose death.

Marijuana is effective at relieving nausea and vomiting, spasticity, appetite loss, certain types of pain, and other debilitating symptoms. And it is extraordinarily safe - safer than most medicines prescribed every day. If marijuana were a new discovery rather than a well-known substance carrying cultural and political baggage, it would be hailed as a wonder drug.

We in this country have to make up our minds -- -- we can not have it both ways: we cannot be both drug-free and free.

I am convinced that there are genuine and valid levels of perception available with cannabis (and probably with other drugs) which are, through the defects of our society and our educational system, un-available to us without such drugs.

I began to study marijuana in 1967... I had not yet learned that there is something very special about illicit drugs. If they don't always make the drug user behave irrationally, they certainly cause many non-users to behave that way.

Marijuana is one of the least toxic substances in the whole pharmacopoeia

I've been smoking marijuana for 44 years now, and ... I think it's a tremendous blessing.

I have come to doubt whether the FDA rules should apply to cannabis. There is no question about its safety. It is one of humanity's oldest medicines, used for thousands of years by millions of people with very little evidence of significant toxic effects. More is known about its adverse effects than about those of most prescription drugs.