Gerald Edelman quotes:

Science is imagination in the service of the verifiable truth, and that service is indeed communal. It cannot be rigidly planned. Rather, it requires freedom and courage and the plural contributions of many different kinds of people who must maintain their individuality while giving to the group.

Each brain is exposed to different circumstances. It's very likely that your brain is unique in the history of the universe.

Your brain develops depending on your individual history. What has gone on in your own brain and its consciousness over your lifetime is not repeatable, ever - not with identical twins, not even with conjoined twins.

Most theoretical work since the proposals of Hebb (1949) and Hayek (1952) has relied upon particular forms of dependent synaptic rules in which either pre- or postsynaptic change is contingent upon closely occurring events in both neurons taking part in the synapse.

The computer is not, in our opinion, a good model of the mind, but it is as the trumpet is to the orchestra - you really need it. And so, we have very massive simulations in computers because the problem is, of course, very complex.

A knowledge of brain science will provide one of the major foundations of the new age to come. That knowledge will spawn cures for disease, new machines based on brain function, further insights into our nature and how we know.

Early human thought proceeded by metaphor,

Evolution works by selection, not by instruction. There is no final cause, no teleology, no purpose guiding the overall process

Consciousness may be seen as the haughty and restless second cousin of morphology. Memory is its mistress, perception its somewhat abused wife, logic its housekeeper, and language its poorly paid secretary

Many cognitive psychologists see the brain as a computer. But every single brain is absolutely individual, both in its development and in the way it encounters the world.

When finally substantiated by scientific means, such a view will allow an individual to see his place in the world with greater clarity-- how he came from the world and how he may contribute to his fellows while he enjoys for a brief time the privilege of consciousness and communication.

Hebb place the Law of Effect at the synaptic level by proposing a correlation model of synaptic modification similar to that of Hayek (1952). This work was seminal in providing a basis for many subsequent theoretical studies . .

Consciousness allows you the capacity to plan.

Since the idea that modification of synaptic function can provide a basis for memory arose shortly after the first anatomical description of the synapse a number of models (Hebb 1949 . . Hayek 1952 . . Kendel 1981) have been proposed in which various cognitive activities are represented by combinations of the firing patterns of individual neurons.

We're inquiring into the deepest nature of our constitutions: How we inherit from each other. How we can change. How our minds think. How our will is related to our thoughts. How our thoughts are related to our molecules.

Hayek made a quite fruitful suggestion, made contemporaneously by the psychologist Donald Hebb, that whatever kind of encounter the sensory system has with the world, a corresponding event between a particular cell in the brain and some other cell carrying the information from the outside word must result in reinforcement of the connection between those cells. These day, this is known as a Hebbian synapse, but von Hayek quite independently came upon the idea. I think the essence of his analysis still remains with us . .

The analogy between the mind and a computer fails for many reasons. The brain is constructed by principles that assure diversity and degeneracy. Unlike a computer, it has no replicative memory. It is historical and value driven. It forms categories by internal criteria and by constraints acting at many scales, not by means of a syntactically constructed program. The world with which the brain interacts is not unequivocally made up of classical categories.